https://www.ceesdekker.net Secrets
https://www.ceesdekker.net Secrets
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Spatial composition facilitates cooperation inside of a social Predicament: empirical proof from the bacterial Group
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[Laughs] ‘It was surely a fantastic risk! At enough time, I was very well conscious that it could go Erroneous and that I could develop into much less thriving, but I just dismissed that. Curiosity has normally been my strongest driving power. And fortunately it all labored out.’
2007, 1st actual-time detection of strand Trade in homologous recombination by RecA; discovery of the reduced persistence duration of finishes of microtubules; and resolved the system of biosensing with carbon nanotubes
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The coiled-coil of your human Rad50 DNA mend protein includes specific segments of greater versatility
All parameters were being the same for each panel Within this video clip, apart from the First placement with the 6hb rod (revealed in blue) over the nanopore. Simulations that terminated early due to translocation from the rod with the pore are marked by a grey track record.
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In 1993, for a young and eager associate professor at Delft College of Technological know-how, I had originally centered the research efforts of my group on measuring the electrical conductance of one conducting-polymer molecule. In just two many years, we had designed a tool wherein a single wire of a phthalocyaninepolysiloxane polymer was linked amongst two carefully spaced metallic nanoelectrodes.
There was one issue even though — we didn't notice any measurable electrical conduction from The only polymer molecules. We concluded that at The only-molecule stage, conducting polymers ended up essentially not these types of great conductors, which was rather disappointing. We Therefore broadened our see to try to locate much more promising molecules.
Tests pseudotopological and nontopological styles for cees dekker SMC-pushed DNA loop extrusion from roadblock-traversal experiments
Cees Dekker is Distinguished College Professor at TU Delft. Skilled to be a physicist, he pioneered nanotechnology with quite a few discoveries on carbon nanotubes within the nineties. Due to the fact 2000, he moved to solitary-molecule biophysics and nanobiology. His recent analysis concentrates on (i) nanopores for protein sequencing; (ii) chromosome framework, especially SMC motor protein; and (iii) developing a living synthetic cell from lifeless molecules. Dekker is surely an elected member of your KNAW and fellow into the APS and also the IOP.
Developments in nanotechnology inside the nineties created constructing electronic units from solitary molecules a chance. Cees Dekker recounts how his group developed a space-temperature transistor depending on just one carbon nanotube.
Solid-point out nanopores have proven to be a remarkably versatile probe for single-molecule analysis of DNA. I'll explain several of our new conclusions – specially DNA knots – and also our initiatives to grow the capabilities of stable-condition nanopores even more, inside the route of single-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.